PUBLICATIONS RECENTES DE L'INSTITUT COCHIN

 

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 Publications récentes des équipes de l'Institut Cochin

 

  • Auer J, Camoin L, Guillonneau F, Rigourd V, Chelbi ST, Leduc M, Laparre J, Mignot TM, and Vaiman D.

Serum profile in preeclampsia and intra-uterine growth restriction revealed by iTRAQ technology.
J Proteomics, 2010 73:1004-1017.                (lien PubMed)
Equipe GD : Vaiman

  • Boulkroun S, Guenin-Mace L, Thoulouze MI, Monot M, Merckx A, Langsley G, Bismuth G, Di Bartolo V, and Demangel C.

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.
J Immunol, 2010 184:1436-44.     (lien PubMed)
Equipe IH : Trautmann-Bismuth et Equipe BIOCIHP : Langsley

  • Lefevre B, Wolf JP, and Ziyyat A.

Sperm-egg interaction: is there a link between tetraspanin(s) and GPI-anchored protein(s)?
Bioessays, 2010 32:143-52.              (lien PubMed)
Equipe GD : Vaiman

  • Terris B, Cavard C, and Perret C.

EpCAM, a new marker for cancer stem cells in hepatocellular carcinoma.
J Hepatol, 2010 52:280-281.               (lien PubMed)
Equipe EMC : Perret

  • Essabbani A, Margottin-Goguet F, and Chiocchia G.

Identification of Clusterin Domain Involved in NF-{kappa}B Pathway Regulation.
J Biol Chem, 2010 285:4273-7.           (lien PubMed)
Equipes IH : Chiocchia et  BIOCIHP : Margottin

  • L'Hote D, Laissue P, Serres C, Montagutelli X, Veitia RA, and Vaiman D.

Interspecific resources: a major tool for quantitative trait locus cloning and speciation research.
Bioessays, 2010 32:132-142.              (lien PubMed)
Equuipe GD : Vaiman

  •  Pavlowsky A, Gianfelice A, Pallotto M, Zanchi A, Vara H, Khelfaoui M, Valnegri P, Rezai X, Bassani S, Brambilla D, Kumpost J, Blahos J, Roux MJ, Humeau Y, Chelly J, Passafaro M, Giustetto M, Billuart P, and Sala C. A

Postsynaptic Signaling Pathway that May Account for the Cognitive Defect Due to IL1RAPL1 Mutation.
Curr Biol, 2010 20:103-115.                    (lien PubMed)
Equipe GD : Chelly

  • Laurent B, Randrianarison-Huetz V, Marchal V, Mayeux P, Dusanter-Fourt I, and Dumenil D.

High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription.
Blood, 2010 115:687-95.                       (lien PubMed)
Equipe IH : Dusanter-Fourt-Cramer et IH : Lacombe-Mayeux

  • Douillard-Guilloux G, Raben N, Takikita S, Ferry A, Vignaud A, Guillet-Deniau I, Favier M, Thurberg BL, Roach PJ, Caillaud C, and Richard E.

Restoration of muscle functionality by genetic suppression of glycogen synthesis in a murine model of Pompe disease.
Hum Mol Genet, 2010 19:684-96           (lien PubMed)
Equipe GD : Maire et GD : Caillaud

  • Lemichez E, Lecuit M, Nassif X, and Bourdoulous S.

Breaking the wall: targeting of the endothelium by pathogenic bacteria.
Nat Rev Microbiol, 2010 8:93-104.             (lien PubMed)
Equipe BIOCIHP : Bourdoulous-Niedergang

  • Verdeguer F, Le Corre S, Fischer E, Callens C, Garbay S, Doyen A, Igarashi P, Terzi F, and Pontoglio M.

A mitotic transcriptional switch in polycystic kidney disease.
Nat Med, 2010 16:106-10                (lien PubMed)
Equipe GD : Pontoglio

  • Ratelade J, Arrondel C, Hamard G, Garbay S, Harvey S, Biebuyck N, Schulz H, Hastie N, Pontoglio M, Gubler MC, Antignac C, and Heidet L.

A murine model of Denys-Drash syndrome reveals novel transcriptional targets of WT1 in podocytes.
Hum Mol Genet, 2010 19:1-15.                   (lien PubMed)
Equipe GD : Pontoglio et Plate forme : Recombinaison Homologue de G. Hamard

  • Jaglin XH, and Chelly J.

Tubulin-related cortical dysgeneses: microtubule dysfunction underlying neuronal migration defects.
Trends Genet, 2009 25:555-66.          (lien PubMed)
Equipe GD : Chelly

  • Mitchell C, Robin MA, Mayeuf A, Mahrouf-Yorgov M, Mansouri A, Hamard M, Couton D, Fromenty B, and Gilgenkrantz H.

Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in mice.
Am J Pathol, 2009 175:1929-37.           (lien PubMed)
Equipe EMC : Gilgenkrantz

  • Gabory A, Ripoche MA, Le Digarcher A, Watrin F, Ziyyat A, Forne T, Jammes H, Ainscough JF, Surani MA, Journot L, and Dandolo L.

H19 acts as a trans regulator of the imprinted gene network controlling growth in mice.
Development, 2009 136:3413-21                      (lien PubMed)
Equipe GD : Vaiman                      

  • Gagnerault MC, Lanvin O, Pasquier V, Garcia C, Damotte D, Lucas B, and Lepault F.

 Autoimmunity during thymectomy-induced lymphopenia: role of thymus ablation and initial effector T cell activation timing in nonobese diabetic mice.
J Immunol, 2009 183:4913-20              (lien PubMed)
Equipe IH : Lucas

  • Zagani R, Hamzaoui N, Cacheux W, de Reynies A, Terris B, Chaussade S, Romagnolo B, Perret C, and Lamarque D.

Cyclooxygenase-2 inhibitors down-regulate osteopontin and Nr4A2-new therapeutic targets for colorectal cancers.
Gastroenterology, 2009 137:1358-66 e1-3.                (lien PubMed)
Equipe EMC : Perret

  • Ragazzon B, Cazabat L, Rizk-Rabin M, Assie G, Groussin L, Fierrard H, Perlemoine K, Martinez A, and Bertherat J. 

Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.
Cancer Res, 2009 69:7278-84.                            (lien PubMed)
Equipe EMC : Bertherat

  • Abou-Khalil R, Le Grand F, Pallafacchina G, Valable S, Authier FJ, Rudnicki MA, Gherardi RK, Germain S, Chretien F, Sotiropoulos A, Lafuste P, Montarras D, and Chazaud B.

Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal.
Cell Stem Cell, 2009 5:298-309.                          (lien PubMed)
Equipe GD : Chelly

  • Tudor D, Derrien M, Diomede L, Drillet AS, Houimel M, Moog C, Reynes JM, Lopalco L, and Bomsel M.

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis.
Mucosal Immunol, 2009 2:412-26.           (lien PubMed)
Equipe BIOCIHP : Bomsel                                                                                    

  • Langevin C, Maidou-Peindara P, Aas PA, Jacquot G, Otterlei M, Slupphaug G, and Benichou S.

Human immunodeficiency virus type 1 Vpr modulates cellular expression of UNG2 via a negative transcriptional effect.
J Virol, 2009 83:10256-63.                                         (lien PubMed)
Equipe BIOCIHP : Bénichou-Benmerah

  • Laurent B, Randrianarison-Huetz V, Kadri Z, Romeo PH, Porteu F, and Dumenil D.

Gfi-1B Promoter Remains Associated with Active Chromatin Marks Throughout Erythroid Differentiation of Human Primary Progenitor Cells.
Stem Cells, 2009 27:2153-2162.                 (lien PubMed)                 
Equipe IH : Porteu

  • Dhaenens M, Fert I, Glatigny S, Haerinck S, Poulain C, Donnadieu E, Hacquard-Bouder C, Andre C, Elewaut D, Deforce D, and Breban M.

Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability.
Arthritis Rheum, 2009 60:2622-2632.                           (lien PubMed)
Equipe IH : Breban-Chiocchia

  • Le Campion A, Gagnerault MC, Auffray C, Becourt C, Poitrasson-Riviere M, Lallemand E, Bienvenu B, Martin B, Lepault F, and Lucas B. 

Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development.
Blood, 2009 114:1784-93.              (lien PubMed)
Equipe IH : Lucas

  •  Eustache F, Mondon F, Canivenc-Lavier MC, Lesaffre C, Fulla Y, Berges R, Cravedi JP, Vaiman D, and Auger J.

Chronic dietary exposure to a low-dose mixture of genistein and vinclozolin modifies the reproductive axis, testis transcriptome, and fertility.
Environ Health Perspect, 2009 117:1272-9.            (lien PubMed)
Equipe : GD Vaiman

  • Tamburini J, Green AS, Bardet V, Chapuis N, Park S, Willems L, Uzunov M, Ifrah N, Dreyfus F, Lacombe C, Mayeux P, and Bouscary D.

Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.
Blood, 2009 114:1618-27.                       (lien PubMed)
Equipe IH : Lacombe-Mayeux

  • Fruman DA, and Bismuth G.

Fine tuning the immune response with PI3K.
Immunol Rev, 2009 228:253-72                  (lien PubMed)
Equipe IH : Trautmann-Bismuth

  • Saillour Y, Carion N, Quelin C, Leger PL, Boddaert N, Elie C, Toutain A, Mercier S, Barthez MA, Milh M, Joriot S, des Portes V, Philip N, Broglin D, Roubertie A, Pitelet G, Moutard ML, Pinard JM, Cances C, Kaminska A, Chelly J, Beldjord C, and Bahi-Buisson N.

LIS1-related isolated lissencephaly: spectrum of mutations and relationships with malformation severity.
Arch Neurol, 2009 66:1007-15.             (lien PubMed)

Equipe GD : Chelly

  • Laguette N, Bregnard C, Bouchet J, Benmerah A, Benichou S, and Basmaciogullari S. 

Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase.
J Virol, 2009 83:7117-28.                       (lien PubMed)
Equipe BIOCIHP : Benichou-Benmerah

  • Celton-Morizur S, Merlen G, Couton D, Margall-Ducos G, and Desdouets C.

The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents.
J Clin Invest, 2009 119:1880-7       (lien PubMed)
Equipe EMC : Gilgenkrantz

  • Nascimbeni M, Perie L, Chorro L, Diocou S, Kreitmann L, Louis S, Garderet L, Fabiani B, Berger A, Schmitz J, Marie JP, Molina TJ, Pacanowski J, Viard JP, Oksenhendler E, Beq S, Abehsira-Amar O, Cheynier R, and Hosmalin A.

Plasmacytoid dendritic cells accumulate in spleens from chronically HIV-infected patients but barely participate in interferon-alpha expression.
Blood, 2009 113:6112-9       (lien PubMed)
Equipe IH : Hosmalin

  • Mitchell RS, Katsura C, Skasko MA, Fitzpatrick K, Lau D, Ruiz A, Stephens EB, Margottin-Goguet F, Benarous R, and Guatelli JC.

Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.
PLoS Pathog, 2009 5:e1000450.        (lien PubMed)
Equipe BIOCIHP : Margottin-Goguet

  •  Goenaga D, Hampe C, Carre N, Cailliau K, Browaeys-Poly E, Perdereau D, Holt LJ, Daly RJ, Girard J, Broutin I, Issad T, and Burnol AF.

Molecular determinants of Grb14-mediated inhibition of insulin signaling.
Mol Endocrinol, 2009 23:1043-51.        (lien PubMed)
Equipe EMC : Burnol,  Equipe EMC : Issad

  • Ramey G, Deschemin JC, and Vaulont S.

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes.
Haematologica, 2009 94:765-772.      (lien PubMed)
Equipe EMC : Vaulont

  • Jaglin XH, Poirier K, Saillour Y, Buhler E, Tian G, Bahi-Buisson N, Fallet-Bianco C, Phan-Dinh-Tuy F, Kong XP, Bomont P, Castelnau-Ptakhine L, Odent S, Loget P, Kossorotoff M, Snoeck I, Plessis G, Parent P, Beldjord C, Cardoso C, Represa A, Flint J, Keays DA, Cowan NJ, and Chelly J.

Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria.
Nat Genet, 2009 41:746-752.          (lien PubMed)
Equipe GD : Chelly

  • Laissue P, Lakhal B, Benayoun BA, Dipietromaria A, Braham R, Elghezal H, Philibert P, Saad A, Sultan C, Fellous M, and Veitia RA.

Functional evidence implicating FOXL2 in non-syndromic premature ovarian failure and in the regulation of the transcription factor OSR2.
J Med Genet, 2009 46:455-7.       (lien PubMed)
Equipe GD : Vaiman

Mutations in regulatory subunit type 1A of cyclic adenosine 5'-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes.
J Clin Endocrinol Metab, 2009 94:2085-91.          ( lien Pub Med)
Equipe EMC : Bertherat

  •  Bertherat J, and Bertagna X.

Pathogenesis of adrenocortical cancer.
Best Pract Res Clin Endocrinol Metab, 2009 23:261-71.    (lien PubMed)
Equipe EMC : Bertherat

  • Horvath A, Korde L, Greene MH, Libe R, Osorio P, Faucz FR, Raffin-Sanson ML, Tsang KM, Drori-Herishanu L, Patronas Y, Remmers EF, Nikita ME, Moran J, Greene J, Nesterova M, Merino M, Bertherat J, and Stratakis CA.

Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors.
Cancer Res, 2009 69:5301-6.             (lien PubMed)
Equipe EMC : Bertherat

  •  Louiset E, Stratakis CA, Perraudin V, Griffin KJ, Libe R, Cabrol S, Feve B, Young J, Groussin L, Bertherat J, and Lefebvre H.

The Paradoxical Increase in Cortisol Secretion Induced by Dexamethasone in Primary Pigmented Nodular Adrenocortical Disease Involves a Glucocorticoid Receptor-Mediated Effect of Dexamethasone on Protein Kinase A Catalytic Subunits.
J Clin Endocrinol Metab, 2009 94:2406-2413.         (lien PubMed)
Equipe EMC : Bertherat

  • Coureuil M, Mikaty G, Miller F, Lecuyer H, Bernard C, Bourdoulous S, Dumenil G, Mege RM, Weksler BB, Romero IA, Couraud PO, and Nassif X.

Meningococcal Type IV Pili Recruit the Polarity Complex to Cross the Brain Endothelium.
Science, 2009 325:83-87.                   (lien PubMed)
Equipe BIOCIHP : Couraud,   Equipe BIOCIHP: Bourdoulous

  • Zinovieva E, Bourgain C, Kadi A, Letourneur F, Izac B, Said-Nahal R, Lebrun N, Cagnard N, Vigier A, Jacques S, Miceli-Richard C, Garchon HJ, Heath S, Charon C, Bacq D, Boland A, Zelenika D, Chiocchia G, Breban M.

Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis.
PLoS Genet. 2009 Jun;5(6):e1000528.      (lien PubMed)
Equipe IH : Chiocchia, Breban,    Plate-forme : séquençage

  • Delhommeau F, Dupont S, Della Valle V, James C, Trannoy S, Masse A, Kosmider O, Le Couedic JP, Robert F, Alberdi A, Lecluse Y, Plo I, Dreyfus FJ, Marzac C, Casadevall N, Lacombe C, Romana SP, Dessen P, Soulier J, Viguie F, Fontenay M, Vainchenker W, and Bernard OA.

Mutation in TET2 in myeloid cancers.
N Engl J Med, 2009 360:2289-301.             (lien PubMed)
Equipe IH  Lacombe-Mayeux

  • Lambert S, Bouttier M, Vassy R, Seigneuret M, Petrow-Sadowski C, Janvier S, Heveker N, Ruscetti FW, Perret G, Jones KS, and Pique C.

HTLV-1 uses HSPG and neuropilin-1 for entry by molecular mimicry of VEGF165.
Blood, 2009 113:5176-85. .             (lien PubMed)
Equipe BIOCIHP  Pique

  • Mastrogiannaki M, Matak P, Keith B, Simon MC, Vaulont S, and Peyssonnaux C.

HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.
J Clin Invest, 2009 119:1159-66.                 (lien PubMed)
Equipe EMC Vaulont

Important role for AMPKalpha1 in limiting skeletal muscle cell hypertrophy.
Faseb J, 2009 23:2264-73.               (lien PubMed)
Equipe EMC : Vaulont  et  Equipe GD : Maire

  • Groussin L, Bonardel G, Silvera S, Tissier F, Coste J, Abiven G, Libe R, Bienvenu M, Alberini JL, Salenave S, Bouchard P, Bertherat J, Dousset B, Legmann P, Richard B, Foehrenbach H, Bertagna X, and Tenenbaum F.

18F-Fluorodeoxyglucose positron emission tomography for the diagnosis of adrenocortical tumors: a prospective study in 77 operated patients.
J Clin Endocrinol Metab, 2009 94:1713-22.                 (lien PubMed)
Equipe EMC Bertherat

  • Mitchell C, Couton D, Couty JP, Anson M, Crain AM, Bizet V, Renia L, Pol S, Mallet V, and Gilgenkrantz H.

Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice.
Am J Pathol, 2009 174:1766-75.                 (lien PubMed)
Equipe EMC Gilgenkrantz, Equipe EMC Perret et Equipe IH Pol

  • Bergamaschi A, Ayinde D, David A, Le Rouzic E, Morel M, Collin G, Descamps D, Damond F, Brun-Vezinet F, Nisole S, Margottin-Goguet F, Pancino G, and Transy C.

The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection.
J Virol, 2009 83:4854-60.                 ( lien PubMed)
Equipe BIOCIHP Margottin

  • Cavard C, Audebourg A, Letourneur F, Audard V, Beuvon F, Cagnard N, Radenen B, Varlet P, Vacher-Lavenu MC, Perret C, and Terris B.

Gene expression profiling provides insights into the pathways involved in solid pseudopapillary neoplasm of the pancreas.
J Pathol, 2009 218:201-209.                 ( lien PubMed)
Equipe EMC Perret et Plate-forme séquençage

  • Brinster S, Lamberet G, Staels B, Trieu-Cuot P, Gruss A, and Poyart C.

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens.
Nature, 2009 458:83-6.                 (lien PubMed)
Equipe  BIOCIHP Poyart

  • Baud V, and Karin M.

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls.
Nat Rev Drug Discov, 2009 8:33-40.                 (lien PubMed)
Equipe  IH  Baud

  • Conche C, Boulla G, Trautmann A, and Randriamampita C.

T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate.
Immunity, 2009 30:33-43.                 (lien PubMed)
Equipe IH  Trautmann-Bismuth

 

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